Pediatric Otola yngology : PrincifAes and Practice Radiation Recall Supraglottitis in a Child

The recrudescence and modification of radiation effects precipitated by the use of chemotherapeutic agents has been reported extensively in the literature. The recall of quiescent radiation effects such as dermatitis, enteritis, esophagitis, pneumonitis, and mucositis has been most commonly associated with dactinomycin (actinomytin D) and doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH) therapy, although other chemotherapeutic agents have been implicated. Radiation recall supraglottitis has been reported previously in a 4i’-year-old adult with diffuse histiocytic lymphoma. We report the first case of radiation recall supraglottitis involving dactinomytin therapy in a child.